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Biossance

100% Squalane Oil.

Biossance 100% Squalane Oil
Serums

About this product

A 100% pure squalane oil designed to provide lightweight hydration without clogging pores.

Type

SerumsOil

Guru Score

80%

Approved

4 experts · Moderate agreement
4Gurus
4Approved
0Mixed
0Skip

What the gurus are saying

The bioengineered squalane (sourced from sugarcane or corn via biotech yeast) gets praise for being lightweight and penetrating well. Reviewers note it's skin-identical, non-comedogenic (won't clog pores), and non-occlusive (won't trap oil), making it safe even during flares like perioral dermatitis. At $65, gurus call it an affordable, sustainably made moisturizer.
Synthesized from 4 expert reviews · most recent take July 2026
Every take, in full

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Approved takes Critical takes Mixed takes Hide sponsored
Approved
"Squalane is skin identical, lightweight, non-occlusive, non-comedogenic. It's one of the safest moisturizing options during a perioral dermatitis flare. Biossance makes excellent squalane products at different price points."
All 2 takes from Dr. Mamina
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"Biossance, I've been so fascinated they use sugarcane to make squalane so like they use sugarcane and then they bioengineer yeast to convert the sugar cane into squalane. It's really cool."
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"Squalane is skin identical, lightweight, non-occlusive, non-comedogenic. It's one of the safest moisturizing options during a perioral dermatitis flare. Biossance makes excellent squalane products at different price points."
Approved
"I also like Biossance Squalane Oil."
Approved
"I use the 100% squalane to shave my legs with, shave under my arms with. I'm happy for the kids to use it. Biossance created hempsqualane, which is a squalane molecule which they derive from corn and then they basically feed the corn to the bacteria, the bacteria produce the squalane and then it's half the size so it goes into the skin more, hydrating, amazing."
Approved
"I love the jojoba and the squalane, but you know what, if you want to be bougie, Biossance has it in a way that doesn't destroy the planet for literally $65."
Common questions

Frequently asked.

What is Biossance 100% Squalane Oil?

A 100% pure squalane oil designed to provide lightweight hydration without clogging pores.

Is Biossance 100% Squalane Oil worth it?

Yes. All 4 gurus who reviewed it give it their stamp of approval, for a Guru Score of 80%.

What is Biossance 100% Squalane Oil's Guru Score?

Biossance 100% Squalane Oil holds a Guru Score of 80%. That is our read on how warmly the experts talk about it, based on the verdicts of 4 expert reviewers we have collected.

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