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Biossance Squalane + Ectoin Overnight Rescue Deep Repair Night Cream.

Biossance Squalane + Ectoin Overnight Rescue Deep Repair Night Cream
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Moisturizers
About this product

A night cream formulated with squalane and ectoin, designed to provide deep repair and nourishment through overnight use.

Full ingredients

Water/​Aqua/​Eau, Glycerin, Squalane, Shorea Stenoptera Seed Butter, Caprylic/​Capric Triglyceride, C12-16 Alcohols, Sodium Acrylates Copolymer, Ectoin, Jojoba Esters, Acetyl Hexapeptide-8, Magnesium Chloride, Palmitic Acid, Hydrogenated Lecithin, Hydroxyethyl Acrylate/​Sodium Acryloyldimethyl Taurate Copolymer, Lecithin, Sorbitan Isostearate, Tocopherol, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Sodium Gluconate

More from Biossance 15 products · Guru Score 85% →

Guru Score

65%

Mixed

Early verdict · Few reviews so far

What the gurus are saying

The easy-to-spread texture genuinely clicked with one reviewer's skin, and a few gurus appreciated how it performs compared to thicker competing overnight creams. However, at around $75, most felt the ingredient list didn't justify the price tag, finding it pleasant enough to finish but not worth repurchasing. Opinions split on whether the formula truly merits that investment.
Synthesized from 3 expert reviews · most recent take October 2026

What they liked

  • Easily spreadable texture
  • Works well for some skin types

What they flagged

  • Expensive for the formula
  • Not a repurchase priority

Type

MoisturizersCream

Key actives

Formula notes

Fragrance-freeNo drying alcohol

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
~Mixed
"I think when I reviewed it I gave it either a 5 out of 10 or a 6 out of 10 but I ended up kind of liking it more than I initially did and it was expensive enough where I thought I should finish it up. So it's just like a moisturizer I just use as like the last step of my evening routine. It was nice I wouldn't repurchase it but was nice enough to finish."
All 4 takes from No BS Beauty
The Story Behind America's Fastest Growing Skincare Company - Many Scandals of The Hut Group
"Which is a new squalling and ECT toin overnight cream"
The Strangest Empties for November - Skincare & Beauty Products I've Finished This Month
"I think when I reviewed it I gave it either a 5 out of 10 or a 6 out of 10 but I ended up kind of liking it more than I initially did and it was expensive enough where I thought I should finish it up. So it's just like a moisturizer I just use as like the last step of my evening routine. It was nice I wouldn't repurchase it but was nice enough to finish."
New Moisturizers First Impressions - Biossance Overnight Cream & Drunk Elephant Bora Barrier Cream
"I think this spreads a little bit easier than the Drunk Elephant, especially if it's meant to be a nighttime cream. I like the texture of it better. [...] It has a [...] short, simple ingredient list, but I'm a fan of the peptide and the ectoin in this one. I'm a fan of the Resveratrol as well. I think this could be a winner."
Biossance 🆕 Squalane + Ectoin Overnight Rescue Deep Repair Night Cream Review, How to, & Dupes
"It's a nice cream, definitely not a must have. I will finish this because I spent probably with taxes 75 bucks on it, so I'm determined to finish it up, but definitely not a must have in terms of value and ingredients. It's a bummer, it's a little bit of a disappointment overall. I just expected a little bit more. At least it's hydrating and things like that. It doesn't pill, it's easy to use, so it's got that going for it."
~Nay
"I feel like I would much prefer to use the Drunk Elephant one see how it goes with that before purchasing this but I do like the Biossance line and I would like to try this but I feel like I'm going to try the Drunk Elephant one first and see how it goes."
~Yay
"The Biossance Squalane Ectoin Overnight Rescue is a very similar moisturizer to the I Unique Beta Glucan 3X Cream, but it's like if you infuse that one with a ton more oil, emolliency and buttery richness. It's just more moisturizing and thicker, but it still has that occlusive protective feel, so it's the right next step as the season transitions for my skin."
Sponsored
All 2 takes from Kelly Driscoll
My Sephora Top 15 Skincare Picks
"This is a really interesting moisturizer from Biossance and this is the one that really clicked with me and my skin type and one that I really enjoy using. This is a cream that is really all about repairing, restoring and strengthening your skin while you sleep. You can use this moisturizer during the day absolutely, part of this is just marketing, it's not solely a nighttime cream."
Everything I'm Actually Putting on My Face in October (What Changed)
"The Biossance Squalane Ectoin Overnight Rescue is a very similar moisturizer to the I Unique Beta Glucan 3X Cream, but it's like if you infuse that one with a ton more oil, emolliency and buttery richness. It's just more moisturizing and thicker, but it still has that occlusive protective feel, so it's the right next step as the season transitions for my skin."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Peptides

Peptides are short protein fragments meant to signal repair. The evidence for them is thinner than for retinoids or vitamin C, and it varies a lot by the specific peptide, so the category is more promising than proven.

Source: NIH, National Library of Medicine

Vitamin E

Vitamin E is an antioxidant, and it is often in a formula to keep the other ingredients stable rather than as the active itself. It pairs well with vitamin C, though on its own the evidence for visible change is limited.

Source: NIH, National Library of Medicine

Frequently asked.

What is Biossance Squalane + Ectoin Overnight Rescue Deep Repair Night Cream?

A night cream formulated with squalane and ectoin, designed to provide deep repair and nourishment through overnight use.

Is Biossance Squalane + Ectoin Overnight Rescue Deep Repair Night Cream worth it?

The gurus mostly approve it, but with enough reservations to keep it in the middle at a Guru Score of 65%.

What is Biossance Squalane + Ectoin Overnight Rescue Deep Repair Night Cream's Guru Score?

Biossance Squalane + Ectoin Overnight Rescue Deep Repair Night Cream holds a Guru Score of 65%. That is our read on how warmly the experts talk about it, based on the verdicts of 3 expert reviewers we have collected.

Who is Biossance Squalane + Ectoin Overnight Rescue Deep Repair Night Cream best for?

Biossance Squalane + Ectoin Overnight Rescue Deep Repair Night Cream is generally suited to dry skin and sensitive skin.

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