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Dermatica Custom Blended Prescription Retinoid.

Dermatica Custom Blended Prescription Retinoid
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Retinoids
About this product

An online dermatology service offering custom-blended prescription retinoid formulas tailored to individual skin concerns, delivered monthly by mail.

More from Dermatica 5 products · Guru Score 99% →

Guru Score

82%

Yay

7 experts · Moderate agreement
!
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Heads up: 4 of the 7 experts here were paid by the brand, leaving 3 unpaid. We have kept this score cautious as a result.

What the gurus are saying

Prescription retinoids genuinely do reverse signs of aging, but the gurus who tried Dermatica found results take time, smoothing texture and fading spots, though subtly over months rather than weeks. The real draw for many is the service itself: an affordable, seamless way to access prescription-strength treatments without visiting a dermatologist in person, especially valuable for those outside the US or unable to access traditional dermatology. The bonus is customization, gurus praise the ability to blend retinoids with other actives like azelaic acid or tranexamic acid for hyperpigmentation, solving multiple concerns in one formula.
Synthesized from 7 expert reviews · most recent take October 2025

What they liked

  • Lightweight formula, absorbs without heaviness

What they flagged

  • Results take 3 to 6 months to show
  • Needs supportive hydrating products alongside it

Type

Retinoids

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
✓Yay
"This is a prescription strength retinoid and the only topical proven to actually reverse signs of aging in the skin, increasing cell turnover, smoothing texture, fading pigmentation, and stimulates new collagen production. But it's not an overnight transformation. [...] I've been using this for 3 months and I can tell you results aren't that fast. [...] I'm peeling in a good way. I think I'm seeing a lot of less texture on my nose and forehead, but the changes are very subtle for now."
✓Yay
"I'm planning on trying it in the new year I want to get this year out the way first"
✓Yay
"Dermatica is great especially if you're in the UK. Those are also smaller and they send them monthly. [...] They also have dark spot formulas so if you have like dark spots and scars they're fantastic."
All 4 takes from Cassandra Bankson
15 Years Of Acne: How I Got My Dream Skin After Having Acne For 15 Years!
"If you're International, Dermatica is great, it's also under 30 bucks."
Finally Addressing Why My Hair Fell Out While Doing My Skincare Routine For The First Time In Months
"I'm going through retinization with dry patches, and it's like I know how to properly start a retinoid in my routine and yet this is still happening."
3 Acne Destroying Skincare Tips I Wish I knew When I was 16
"Dermatica is great especially if you're in the UK. Those are also smaller and they send them monthly. [...] They also have dark spot formulas so if you have like dark spots and scars they're fantastic."
Which Retinoid is Best for Your Skin Type?
"You can get a custom blended prescription [...] from dermatica where you're getting the full strength [...] retinoid [...] blended with other ingredients such as salicylic acid or tranexamic acid if you have hyperpigmentation or azelaic acid if you have rosacea. I like dermatica."
✓Yay
"I cannot stress enough how much Dermatica has changed my skin noticeably over the years I've been using them. The changes I want to see in my skin were achievable and realistic. I want to see a more even skin tone, a more even texture. I want to fade dark spots that hang around my skin after I have like a blemish or something like that. And then I also want some preventative measures in there as well too, reducing the appearance of fine lines also. I am not a skincare expert by any means."
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All 4 takes from Robert Welsh
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"I have been using Dermatica for almost, it's coming up to three months now and I have seen a vast improvement in my skin."
This Is NOT Real Skin!! | The "real skin" lie
"I have been using Dermatica for a really, really long time. I think it's years now. Dark spots on my skin became a lot less visible, my skin tone started evening out a little bit more. And areas on my face that were typically quite textured on my cheeks, around my nose, really did smooth out. I stopped using Dermatica for like a month for no reason other than I think I was testing some other products. And I really, really did notice the difference. Dermatica personalize a formula for you."
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"It's actually got me doing something I probably wouldn't have been doing without this product. I haven't stopped being impressed with the way this product is changing my skin. Makeup sits so much better on my skin. The texture of my skin has vastly improved. [...] This is definitely something that's going to help you out towards your skincare goals without having to be one of those product ingredient geniuses. Someone else has done it for you."
A TOTAL FLOP FOR BENEFIT?? | POREfessional Foundation wear test on oily skin
"I cannot stress enough how much Dermatica has changed my skin noticeably over the years I've been using them. The changes I want to see in my skin were achievable and realistic. I want to see a more even skin tone, a more even texture. I want to fade dark spots that hang around my skin after I have like a blemish or something like that. And then I also want some preventative measures in there as well too, reducing the appearance of fine lines also. I am not a skincare expert by any means."
✓Yay
"At least in the USA it's not easy to get and if you know anything about dermatologists they are not cheap. My personal favorite way of getting tretinoin is through Dermatica. The great thing about Dermatica is that they're a digital dermatology provider so you can get your tretinoin prescription just through your phone. You'll be paired with a dermatology provider, they'll discuss your concerns with you and then give you a custom prescription based off of what you need."
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All 5 takes from Hyram
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"My personal favorite provider of this past year has been Dermatica. Dermatica is a Dermatology service that's online where you pay for a monthly subscription of a custom formula that's made by a Dermatology provider with prescription ingredients. They can fully customize based on your preference. I've tried a few of these providers and while I think they're each good in their own way, for tretinoin I've definitely enjoyed using Dermatica the most as I can really see the results."
The BEST Skin Care of 2024 for Acne & Acne Scars
"You can go to a dermatologist to get a tretinoin prescription or you can do what I do which is use Dermatica, which is an online dermatology provider where they will send you your prescription in the mail and it makes it super easy and way more efficient than having to go to your dermatologist. I've tried a few different delivery dermatology providers but Dermatica has consistently been my favorite one and where I've really noticed the best results from my tretinoin use."
The BEST of 2024 for Wrinkles & Aging!
"At least in the USA it's not easy to get and if you know anything about dermatologists they are not cheap. My personal favorite way of getting tretinoin is through Dermatica. The great thing about Dermatica is that they're a digital dermatology provider so you can get your tretinoin prescription just through your phone. You'll be paired with a dermatology provider, they'll discuss your concerns with you and then give you a custom prescription based off of what you need."
Skin Aging: Your Questions Answered!
"There's a lot of great online dermatology providers like Curology or Dermatica, both of which I've used and loved. [...] I definitely recommend using a service like Dermatica, that's what I personally use right now for my tretinoin, and I know and trust you're going to see a lot more powerful results at a way lower price point than buying Mary Kay products."
ACNE | Answering Your Most Asked Questions!
"I personally love prescription skincare services like Dermatica, they make it super easy to get you a customized tretinoin product. I recommend using a service like Dermatica because they're able to connect you with a dermatology specialist who can prescribe you formulations or products with prescription ingredients that work a lot better than anything you'd find over the counter."
✓Yay
"I have used Curology, I've used Agency, and I've also used Dermatica, and all three of them I've had really positive, good success with. I've also been able to combine my azelaic acid and tretinoin with all three of these services. Tretinoin is helping my skin and helping to communicate to my cells to behave in a more youthful manner."
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All 3 takes from Kelly Driscoll
All About Azelaic Acid + Product Recs!
"Both are really great, curology a little bit more focused on acne, Apostrophe a little bit more focused on anti-aging, but you can still get tretinoin with curology. So then I moved over to Apostrophe and I have my azelaic acid and my tretinoin, and then recently I've been trying out Dermatica Custom Blended Prescription Retinoid because I just kind of wanted to expand my horizons a little bit."
10 Top Tips for Tretinoin | AD ft Dermatica
"I love online services because it's easy, it's affordable and it's really accessible. I also love that they do compound formulas at Dermatica."
5 Ingredients That Changed My Skin for the Better!
"I have used Curology, I've used Agency, and I've also used Dermatica, and all three of them I've had really positive, good success with. I've also been able to combine my azelaic acid and tretinoin with all three of these services. Tretinoin is helping my skin and helping to communicate to my cells to behave in a more youthful manner."
✓Yay
"They make the process so incredibly seamless and easy for you to access your dermatologist, get appropriate care, and get strength as medication that wouldn't necessarily be readily available over the counter. Sometimes your hyperpigmentation or your acne or whatever other condition you are trying to treat really needs more than what over-the-counter products can offer."
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Frequently asked.

What is Dermatica Custom Blended Prescription Retinoid?

An online dermatology service offering custom-blended prescription retinoid formulas tailored to individual skin concerns, delivered monthly by mail.

Is Dermatica Custom Blended Prescription Retinoid worth it?

Yes. All 7 gurus who reviewed it give it their stamp of approval, for a Guru Score of 82%.

What is Dermatica Custom Blended Prescription Retinoid's Guru Score?

Dermatica Custom Blended Prescription Retinoid holds a Guru Score of 82%. That is our read on how warmly the experts talk about it, based on the verdicts of 7 expert reviewers we have collected.

Cheaper alternatives the gurus rate.

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