Dermelect Smooth Upper Lip and Perioral Anti-Aging Treatment

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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✓Yay

"It is by Dermelect, it is called the Smooth Upper Lip and [...] Perioral Anti-Aging Treatment. The reason that I specifically love and recommend this one, well there's really five main reasons. First of all, this has Matrixyl 3000 in it, which is the most powerful blend of peptides that can build new collagen. So that's what's going to plump the lip up, prevent those wrinkles from forming, and then help plump and kind of smooth out those fine lines."

All 2 takes from The Budget Dermatologist

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"This is the Smooth Upper Lip and Perioral Anti-aging Treatment, for those vertical lip lines above the mouth. It has matrixyl 3000 in it, and I like this one for these lines because those lines are so hard to correct once they get etched in, so prevention is really important. That is what I use this for, and then it can even reverse and make those look a little bit more subtle in some people if your lines are not super advanced."

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"It is by Dermelect, it is called the Smooth Upper Lip and [...] Perioral Anti-Aging Treatment. The reason that I specifically love and recommend this one, well there's really five main reasons. First of all, this has Matrixyl 3000 in it, which is the most powerful blend of peptides that can build new collagen. So that's what's going to plump the lip up, prevent those wrinkles from forming, and then help plump and kind of smooth out those fine lines."

Beyond50Skin

32k subs

✓Mixed

"I haven't noticed a huge difference, but it is slightly plumping. That said, I do have a little problem with the applicator. This little rollerball keeps [...] kind of coming off, and the product comes out really quickly, so you need to be very gentle if [...] you're trying to dispense a small amount. It comes out very quickly and you can't lock it, so when I store it a lot of the product gets into the cap. There are a few packaging problems with this in my opinion."

All 2 takes from Beyond50Skin

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"I haven't noticed a huge difference, but it is slightly plumping. I have a little problem with the applicator though. This little rollerball keeps coming off, [...] and when you're trying to dispense a small amount it comes out really quickly, so you have to be very gentle. You can't lock it, so when I store it a lot of the product gets into the cap. There are a few packaging problems with this in my opinion."

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"I haven't noticed a huge difference, but it is slightly plumping. That said, I do have a little problem with the applicator. This little rollerball keeps [...] kind of coming off, and the product comes out really quickly, so you need to be very gentle if [...] you're trying to dispense a small amount. It comes out very quickly and you can't lock it, so when I store it a lot of the product gets into the cap. There are a few packaging problems with this in my opinion."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Retinoids

Retinoids are among the best studied ingredients in dermatology, with solid evidence for acne and for the fine lines and rough texture that come from sun exposure. Dryness and flaking in the first few weeks are common and usually settle.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Peptides

Peptides are short protein fragments meant to signal repair. The evidence for them is thinner than for retinoids or vitamin C, and it varies a lot by the specific peptide, so the category is more promising than proven.

Source: NIH, National Library of Medicine

Frequently asked.

What is Dermelect Smooth Upper Lip and Perioral Anti-Aging Treatment?

A targeted treatment designed to address fine lines and aging around the lips and mouth area, with plumping properties.

Is Dermelect Smooth Upper Lip and Perioral Anti-Aging Treatment worth it?

Mostly yes. 1 of the 2 gurus who reviewed it give it their stamp of approval, for a Guru Score of 76%.

What is Dermelect Smooth Upper Lip and Perioral Anti-Aging Treatment's Guru Score?

Dermelect Smooth Upper Lip and Perioral Anti-Aging Treatment holds a Guru Score of 76%. That is our read on how warmly the experts talk about it, based on the verdicts of 2 expert reviewers we have collected.