Is Grande Cosmetics GrandeLASH-MD worth it?

Mostly no. Only 2 of the 9 gurus who reviewed it approve, which leaves it a Guru Score of 49%.

What is Grande Cosmetics GrandeLASH-MD's Guru Score?

Grande Cosmetics GrandeLASH-MD holds a Guru Score of 49%. That is our read on how warmly the experts talk about it, based on the verdicts of 9 expert reviewers we have collected.

Grande Cosmetics

Grande Cosmetics GrandeLASH-MD.

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About this product

A lash and brow growth serum containing prostaglandin analogs and panthenol, designed to enhance lash and eyebrow thickness and length.

Full ingredients

Water/Aqua/Eau, Panthenol, Glycerin, Sodium Citrate, Leuconostoc/Radish Root Ferment Filtrate, Alanine, Alcohol, Aloe Barbadensis Leaf Juice, Arctostaphylos Uva-Ursi Leaf Extract, Arginine, Aspartic Acid, Calcium Gluconate, Caprylyl Glycol, Chamomilla Recutita (Metricaria) Flower Extract, Ethylhexylglycerin, Gluconolactone, Glycine, Hexylene Glycol, Histidine, Honey Extract/Mel/Extrait De Miel, Hydrolyzed Glycosaminoglycans, Hydrolyzed Yeast Extract, Hydroxyethylcellulose, Isoleucine, Isopropyl Cloprostenate, Magnesium Ascorbyl Phosphate, Panax Ginseng Root Extract, Pca, Phenylalanine, Polysorbate 20, Proline, Propylene Glycol, Serine, Sodium Hyaluronate, Sodium Lactate, Sodium PCA, Threonine, Tocopheryl Acetate

Guru Score

49%

Nay

9 experts · Strong agreement

What the gurus are saying

Prostaglandin analogs in this serum drive visible lash and brow growth, but the tradeoff is real: irritation, hyperpigmentation around the eyes, and unwanted hair growth on sensitive areas appear regularly enough that the FDA has warned the brand about transparency. Growth typically shows within weeks, though some find it works better on brows than lashes. Those considering it should know these side effects can start as early as eight weeks and may be permanent, and gurus suggest patch-testing first and using it only short-term before specific events rather than continuously.

Synthesized from 9 expert reviews · most recent take July 2026

What they flagged

Unregulated prostaglandin analogs
Dry eyes and redness
Permanent eyelid and iris discoloration

Type

Drops & dropper

Key actives

Vitamin C Hyaluronic acidVitamin E

Formula notes

Fragrance-freeContains drying alcohol

Where to buy

Sephora → Ulta → Amazon → Google →

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored

Doctorly

3.59M subs

✕Mixed

"There are also some over-the-counter prostaglandin analogs, like the ones in Grandelash and many others, and people also notice inflammatory effects and hyperpigmentation effects with them, and they can change your eye color. But they're extremely effective, and people are generally quite happy with them. Keep it directed with a spoolie on the eyebrows and you should see some growth with it."

Beyond50Skin

32k subs

✕Nay

"I used Grande lash didn't really help much"

Dr. Jenny Liu

324k subs

✕Nay

"Grande lash contains a prostaglandin analog, a common one is called isopropyl cloprostenate. There are many other ones, but this is a common one and it can be a problem because consumers don't know that, and when they're using it they may not be expecting this irritation and hyperpigmentation that may occur. The irritation and hyperpigmentation have been reported so much that the FDA has actually issued warning letters to the brand basically informing them they need to be fully transparent."

AliceintheRabbitHole

59k subs

✕Nay

"I do have my own experiences with these, and I won't use them anymore, I got irritation."

All 2 takes from AliceintheRabbitHole

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"I do have my own experiences with these, and I won't use them anymore, I got irritation."

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"I also experienced unwanted hair growth on my tear duct from the product migrating, which I'd have to pluck with tweezers, and that is extremely painful. It is because of these cons that I have an entire unopened box of this that I just let expire, I'm not going to use it anymore. My advice, if I could go back, would be to only use it short term for a couple of months before a specific event and then stop, not use it continuously the way I did."

The Budget Dermatologist

724k subs

✕Nay

"The problem is that women don't realize what they're putting on their lashes and don't know to watch for these side effects, so they may not stop using it even when complications begin. These side effects start appearing as early as eight weeks of use and can be permanent."

Dr Dray

2.69M subs

✕Nay

"My concern with these is always that they can have prostaglandin analog like compounds in them that definitely can cause dry eyes, and there are cases of people getting hyperpigmentation around the eyes related to these non-prescription lash enhancing serums, and they also can cause eye redness. There's one concerning rare side effect, more common in people actually using prostaglandin analogues to treat glaucoma, which is atrophy of the fat around the eye and a sunken eye appearance."

Cassandra Bankson

2.46M subs

✕Yay

"The lash serum is really good. If you want to grow your lashes, if you want to try it, DermAngelo has spoken a lot about it. He really likes it. I was not into it and he was the one that was like convincing me. It worked. It was good."

All 2 takes from Cassandra Bankson

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"Even though this is a slightly different active ingredient, this still has the prostaglandin analog in it. Even if scientists and doctors and researchers don't know exactly how they work, we know that they can cause changes in pigmentation, we know that they can cause changes in the growth of lashes, and yeah, we know that in some people they can cause some of the fat in the skin to kind of deteriorate."

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HotandFlashy

1.23M subs

✕Nay

"I finished up a tube of Grande Lash. [...] This was sent in PR from Amazon, so I thought I'd give it a try. This does have a prostaglandin analog in it, but I gotta say this didn't work for me as well as my RevitaLash does. I've probably been using this for about six months, that's how long it takes to go through one of these. I use it on my brows and my lashes. It did really well on my brows. My brows seem to be holding in more, but they didn't lose any ground."

Dr. Shereene Idriss

1.73M subs

✕Yay

"Grande Lash has panthenol in it to help make your hair fuller more elastic more supple especially on your eyebrows because you want to tame them and your eyelashes."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Vitamin C

Topical vitamin C is an antioxidant with reasonable evidence for dullness and uneven tone. It breaks down in light and air, so how a product is formulated and packaged matters as much as the percentage on the front.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Vitamin E

Vitamin E is an antioxidant, and it is often in a formula to keep the other ingredients stable rather than as the active itself. It pairs well with vitamin C, though on its own the evidence for visible change is limited.

Source: NIH, National Library of Medicine