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La Roche-Posay

La Roche-Posay Effaclar Duo.

About this product

A La Roche-Posay acne treatment that combines benzoyl peroxide with lipohydroxy acid, designed to treat existing blemishes and help prevent new breakouts on acne-prone skin.

Full ingredients

Aqua/​Water, Glycerin, Dimethicone, Isocetyl Stearate, Niacinamide, Isopropyl Lauroyl Sarcosinate, Silica, Ammonium Polyacryloyldimethyl Taurate, Methyl Methacrylate Crosspolymer, Potassium Cetyl Phosphate, Sorbitan Oleate, Zinc Pca, Glyceryl Stearate SE, Isohexadecane, Sodium Hydroxide, Myristyl Myristate, 2-Oleamido-1,3-Octadecanediol, Aluminum Starch Octenylsuccinate, Mannose, Poloxamer 338, Disodium EDTA, Capryloyl Salicylic Acid, Caprylyl Glycol, Vitreoscilla Ferment, Xanthan Gum, Polysorbate 80, Acrylamide/​Sodium Acryloyldimethyltaurate Copolymer, Salicylic Acid, Piroctone Olamine, Parfum/​Fragrance

More from La Roche-Posay 61 products · Guru Score 91% →

Guru Score

76%

Yay

6 experts · Moderate agreement

What the gurus are saying

Benzoyl peroxide plus lipohydroxy acid is the pairing reviewers keep coming back to, and most love it as a spot treatment for pimples and closed comedones. The catch is that it's strong: expect dryness, irritation if you use it all over, and bleached fabrics or hair. A thin layer is the suggestion, and deep cystic acne needs professional care instead.
Synthesized from 6 expert reviews · most recent take April 2026

What they liked

  • Light lotion texture, absorbs quickly
  • Benzoyl peroxide and LHA target acne bacteria
  • Affordable and widely available

What they flagged

  • Very drying and can bleach fabrics and hair

Best for

Type

Formula notes

Contains fragranceNo drying alcohol

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
✓Yay
"This moisturizer is so good and my husband also loves it so much."
✓Yay
"My other recommendation for brand in the adapalene 0.1% category is definitely the La Roche-Posay Effaclar Duo. This is similar formula to adapalene from different gel but it's a little bit gentler base with that soothing thermal water from La Roche-Posay."
✓Yay
"La Roche-Posay Effaclar Duo contains 5.5% micronized benzoyl peroxide formulated in a more gentle way along with lipohydroxy acid, which is a more gentle form of salicylic acid that can also help to exfoliate. It's in a light lotion texture that's very easy to apply, absorbs very quickly with minimal residue."
All 2 takes from Dr. Jenny Liu
Acne 101: review and treatment tips from a dermatologist | Dr. Jenny Liu
"La Roche-Posay Effaclar Duo contains 5.5% micronized benzoyl peroxide formulated in a more gentle way along with lipohydroxy acid, which is a more gentle form of salicylic acid that can also help to exfoliate. It's in a light lotion texture that's very easy to apply, absorbs very quickly with minimal residue."
How to treat BODY ACNE - Back, Chest, & More | Dr. Jenny Liu
"La Roche-Posay Effaclar has benzoyl peroxide, I believe it's 5.5%, and also has a little bit of beta hydroxy acid that works really well too."
✓Yay
"This is a solid product, only 30 something bucks you can get at your local store like say at Target or Amazon. It's a really nice product to consider to add to your regimen. The only downside would really be if your acne is out of its league, you've got to go see a dermatologist. It's not a magic bullet. If you have deep cystic bumps, that's something you'd need to see a dermatologist for. This is good for superficial acne, but it's a great product."
All 4 takes from Dr. Daniel Sugai
Dermatologist Reviews: Rating My Medical Assistant's 20+ Year Old Skincare Routine!
"I used to use the La Roche-Posay Effaclar Duo and I found that it packed such a powerful punch that it really destroyed acne but then left me with a kind of a red ring around that sometimes is so bad that I'd have to use a topical corticosteroid to get it to go away which you're not really supposed to use on your face."
Dermatologist Reviews: The Viral La Roche-Posay Effaclar Duo- is it worth the hype?
"This is a solid product, only 30 something bucks you can get at your local store like say at Target or Amazon. It's a really nice product to consider to add to your regimen. The only downside would really be if your acne is out of its league, you've got to go see a dermatologist. It's not a magic bullet. If you have deep cystic bumps, that's something you'd need to see a dermatologist for. This is good for superficial acne, but it's a great product."
Dermatologist Explains: How to Mix Skincare Ingredients
"If you had a benzo peroxide spot treatment say the La Roche-Posay Effaclar Duo with LHA plus benzoyl peroxide I would not combine that with the retinoid. I just keep that separate."
Skincare Mistakes and Trends of the Year
"The luros effaclar would be a nice option and then apply your retinoid whether it's prescription tretinoin over the counter retinol or adapalene and then apply your moisturizer always apply a moisturizer after your retinoid"
✓Yay
"This is a hero product from La Roche-Posay that I've been recommending for a while now. It's got 5.5% benzoyl peroxide, which is a wonderful ingredient for acne. It's anti-inflammatory and targets the bacteria that causes acne, so it will help fight off existing breakouts and prevent breakouts in the future. Unfortunately, it's very drying and it does bleach fabrics if it comes in contact with your skin and can bleach your hair if it comes in contact with your hair."
All 2 takes from Dr Dray
Drugstore Skincare Gems You Need To Know About!
"This reminds me of the La Roche-Posay Effaclar Duo with the benzoyl peroxide 5.5% at $32. Benzoyl peroxide is good for acne breakouts but it can be drying though."
LA ROCHE POSAY SKIN CARE REVIEWS 🎄12 DAYS OF SKIN CARE @DrDrayzday​
"This is a hero product from La Roche-Posay that I've been recommending for a while now. It's got 5.5% benzoyl peroxide, which is a wonderful ingredient for acne. It's anti-inflammatory and targets the bacteria that causes acne, so it will help fight off existing breakouts and prevent breakouts in the future. Unfortunately, it's very drying and it does bleach fabrics if it comes in contact with your skin and can bleach your hair if it comes in contact with your hair."
✓Yay
"I love La Roche-Posay Effaclar Duo, the US version. It's really great for closed comedones because it's got both benzoyl peroxide and lipohydroxy acid, which are both comedolytic."
Sponsored
All 5 takes from Doctorly
The World's Most Dangerous Pimple Pop
"One of our favorite products is the La Roche-Posay Effaclar Duo which has both benzoyl peroxide and lipohydroxy acid in it. These are the type of products you want to look for to actually spot treat acne."
Black Friday Deals and Skincare Q&A
"I love La Roche-Posay Effaclar Duo, the US version. It's really great for closed comedones because it's got both benzoyl peroxide and lipohydroxy acid, which are both comedolytic."
2023's BEST Products For Acne | Doctorly Reviews
"La Roche-Posay Effaclar Duo has the active ingredients of benzoyl peroxide and lipohydroxy acid. It's a spot treatment but it can be used all over the face on any acne prone skin. You just put a thin layer and it's great as a reactive treatment to help those pimples that pop up. Conversely, if you actually use it on acne prone skin it is a prophylactic treatment to help prevent acne from popping up."
Product We LOVE and HATE from La Roche-Posay | Doctorly Reviews
"If you have acne and you're looking to spot treat, this is a hero combination hero product for you. It has benzoyl peroxide plus lipohydroxy acid in it, and that combination is incredible, especially for spot treating acne. You can certainly use it all over the face, but again it could be irritating for a lot of people, so especially as a spot treatment, it's one of the phenomenal products from La Roche-Posay."
BEST ACNE SPOT TREATMENTS | DOCTORLY AWARDS
"Now you start comboing ingredients, we're like in this whole new space. I [...] think it can be effective. Two effective ingredients. This is a [...] strong product. It can be irritating for people when you're using it all over the face, especially in the comments people are like, this either completely cleared my skin or it was too irritating for me. [...] But as a spot treatment, I think this is going to be very, very effective. I like this too."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Niacinamide

Niacinamide has evidence behind it for redness, uneven tone and supporting the skin barrier, and it is usually well tolerated even by skin that reacts to most things.

Source: DermNet

Salicylic acid

Salicylic acid dissolves in oil, so it can get into a pore rather than just working on the surface. That is why it has long-standing evidence for blackheads and milder acne.

Source: DermNet

Frequently asked.

What is La Roche-Posay Effaclar Duo?

A La Roche-Posay acne treatment that combines benzoyl peroxide with lipohydroxy acid, designed to treat existing blemishes and help prevent new breakouts on acne-prone skin.

Is La Roche-Posay Effaclar Duo worth it?

Yes. All 6 gurus who reviewed it give it their stamp of approval, for a Guru Score of 76%.

What is La Roche-Posay Effaclar Duo's Guru Score?

La Roche-Posay Effaclar Duo holds a Guru Score of 76%. That is our read on how warmly the experts talk about it, based on the verdicts of 6 expert reviewers we have collected.

Who is La Roche-Posay Effaclar Duo best for?

La Roche-Posay Effaclar Duo is generally suited to acne-prone skin.

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