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Melanotan

Melanotan II.

About this product

Melanotan 2 is a synthetic peptide injection marketed to darken skin tone and suppress appetite by stimulating melanin production, typically sourced from unregulated black market suppliers.

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Guru Score

47%

Nay

3 experts · Moderate agreement

What the gurus are saying

Both experts reviewing this warn it away entirely. The peptide requires sun exposure to work and accelerates sunspot and mole formation, raising melanoma risk substantially. Common side effects include nausea, vomiting, fatigue, and flushing; men often report painful, persistent spontaneous erections. Critically, it is not legally approved in the US, Canada, or Europe, meaning you are injecting an untested, unregulated substance of unknown purity, potency, and contamination. There is no antidote if harm occurs. Dermatologists and doctors consulted recommend staying away from it entirely.
Synthesized from 3 expert reviews · most recent take June 2026

What they flagged

  • Causes nausea, stomach cramps, flushing, fatigue
  • Linked to serious kidney damage and priapism
  • Documented cases connecting use to melanoma

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
Hyram
Hyram
4.34M subs
✕Nay
"I have not seen a single person look good with their new tan."
208SkinDoc
208SkinDoc
2.10M subs
✕Nay
"There are also multiple published case reports linking Melanotan use to melanoma, and because it directly stimulates your melanocytes, the exact cells that become melanoma, this is the reason I would never recommend this peptide to anyone. It is an unregulated, non-FDA-approved product usually sold as a powder online with no quality control and no standardized dosing, so people end up having to be their own chemist calculating their own dose, and the reality is this is not worth the risk."
All 2 takes from 208SkinDoc
The Risks of Melanotan No One is Telling You About!
"There are also multiple published case reports linking Melanotan use to melanoma, and because it directly stimulates your melanocytes, the exact cells that become melanoma, this is the reason I would never recommend this peptide to anyone. It is an unregulated, non-FDA-approved product usually sold as a powder online with no quality control and no standardized dosing, so people end up having to be their own chemist calculating their own dose, and the reality is this is not worth the risk."
Stop Taking Melanotan II... Dermatologist Breaks It Down
"Most people are buying it off unregulated websites where you can't guarantee the safety or purity of the product. The spray version isn't safer either, it's probably less effective than the injection form, and the convenience actually makes it more dangerous because it's more accessible to people. This is a risky peptide and I don't encourage its use. If you're on it, stop and go get checked by a dermatologist."
Doctor Youn
Doctor Youn
5.57M subs
✕Nay
"For me it don't work so well. [...] The interesting thing about melanotan is that technically now what people use to darken their skin is called melanotan 2 and this is actually a black market product it is not available for use in Europe Canada or the United States it's not technically legal for use yet people are injecting it under their skin as a way to make their skin darker there are major risks that can be associated with this injection including skin cancer."

Frequently asked.

What is Melanotan Melanotan II?

Melanotan 2 is a synthetic peptide injection marketed to darken skin tone and suppress appetite by stimulating melanin production, typically sourced from unregulated black market suppliers.

Is Melanotan Melanotan II worth it?

Mostly no. None of the 3 gurus who reviewed it came away sold, leaving it a Guru Score of 47%.

What is Melanotan Melanotan II's Guru Score?

Melanotan Melanotan II holds a Guru Score of 47%. That is our read on how warmly the experts talk about it, based on the verdicts of 3 expert reviewers we have collected.

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