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OneSkin

OneSkin OS-01 Eye Topical Supplement.

#22 in Eye CareSee the ranking →
About this product

A peptide-rich eye cream formulated with OneSkin's proprietary OS-01 peptide to address fine lines, wrinkles, and skin firmness around the delicate eye area.

Full ingredients

Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, D-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, SH-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/​Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum

More from OneSkin 10 products · Guru Score 94% →

Guru Score

78%

Yay

7 experts · Moderate agreement

What the gurus are saying

The higher concentration of OS-01 peptide in this eye cream earns consistent praise for visibly plumping fine lines and improving skin texture, with gurus noting it feels creamy and hydrating without heaviness. Most gurus see real results on crepey, aging skin around the eyes, though the hefty price tag gives some pause, and one expert cautions that peptides alone won't turn back time without other actives in your routine. Best for those willing to commit daily and patch-test first, since the eye area is delicate.
Synthesized from 7 expert reviews · most recent take May 2026

What they liked

  • Works well under makeup
  • Lasts several weeks per bottle

What they flagged

  • Pump dispenses too much product at once
  • Product hardens inside the pump opening
  • Expensive for unproven results

Best for

Type

Eye CareCream

Formula notes

Fragrance-freeContains drying alcohol

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
✓Mixed
"The eye cream I'm using right now is the OneSkin OS-01 Eye Topical Supplement. You might wonder why because I said in my review that I wouldn't spend that much money on it and I still stand by that. But it has a lovely texture. I really enjoy how it feels on the skin. So, no need to toss it despite still standing to the fact that I wouldn't repurchase it."
All 2 takes from Doctor Anne
Spring Skincare Routine 2026: What I Changed for Acne, Sensitivity & Aging Skin | Doctor Anne
"The eye cream I'm using right now is the OneSkin OS-01 Eye Topical Supplement. You might wonder why because I said in my review that I wouldn't spend that much money on it and I still stand by that. But it has a lovely texture. I really enjoy how it feels on the skin. So, no need to toss it despite still standing to the fact that I wouldn't repurchase it."
OneSkin OS 01 EYE Topical Supplement Review: Are Zombie Cells Making You look Older? | Doctor Anne
"It [...] has a lovely texture and a really nice ingredient list, but for me doesn't warrant the hefty price tag of 124 € a bottle. The story behind it is nice, but in my opinion not convincing enough to pay that much, and after using it consistently for two months every night, my eyes don't look any less aged than they did before."
✓Yay
"OneSkin also makes an eye cream which I like but my favorite of all time and it's expensive but man it's good."
All 3 takes from Darnell Cox | 50+ Healthy Aging Expert
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"OneSkin also makes an eye cream which I like but my favorite of all time and it's expensive but man it's good."
All of your pressing questions answered in today’s Instagram live show!
"This one by OneSkin uses a peptide OS-01. It helps with all the zombie and senescent cells. It's amazing. But this alone is not an active ingredient; peptides alone are not enough for your skin. [...] I'm obsessed with this brand OneSkin because of the way that it's working. I swear it's repaired my skin."
All of your pressing questions answered in today’s Instagram live show!
"This one by OneSkin uses a peptide OS01, it helps with all the zombie and senescent cells, it's amazing. But this alone is not an active ingredient. Peptides alone are not enough for your skin. [...] I'm obsessed with this brand, OneSkin, because they're really the way that it's..."
✓Yay
"I used it repeatedly for over a year and then I started using the eye cream and the face cream because I'm a huge eye cream person anyway and the very first time I used it I got on that day and I ordered another one. It's got that consistency that I like, the thickness. It's everything that I wanted in a cream. So I'm kind of hooked on it."
All 5 takes from Beyond50Skin
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"Their eye cream has the proprietary peptide just like the facial supplement does. It's a little bit thicker but it has a more potent amount because this area of our skin is a little bit different than the rest of our face. They also decided to increase the amount of OS1 peptide and the potency of the eye cream because this is the area that really crinkles and wrinkles more than any other area. The OS1 peptide helps with our senescent cells."
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"I put away my Dermatology eye cream that I love and I'm using this one. [...] These have been lasting, I'm in it 5 weeks and they feel like maybe they're 2/3 done. [...] This is a little bit more concentrated than the facial topical serum."
Thin Deflated LIPS OVER 50? Do This Now!
"I've been using the OneSkin eye cream twice a day along with their moisturizer. Both formulas have their OS-01 peptide that's supposed to help combat senescent cells or our aging dying cells. I really like the formulas, they're super hydrating."
2025 Body Care for Crepey Skin Over 50 | Holy Grails, New Finds & OneSkin Results!
"I used it repeatedly for over a year and then I started using the eye cream and the face cream because I'm a huge eye cream person anyway and the very first time I used it I got on that day and I ordered another one. It's got that consistency that I like, the thickness. It's everything that I wanted in a cream. So I'm kind of hooked on it."
6 Months of Skincare Empties | My Husband’s 1st Routine in 60 Years + Results
"I like this, but I actually saw more difference in their topical face supplement and body supplement than I did. So I'm kind of on the fence whether I'll repurchase this because it's definitely a bougie buy."
✓Yay
"I do like eye products that have caffeine or a higher concentration of peptide. For example, OneSkin OS-01 Eye Topical Supplement has a higher concentration of peptides in their eye products because this is very thin delicate skin. It's the thinnest skin of our body, the eyelid skin, so we have to take care of that and you do need specialized products for that area."
✓Yay
"Eye products are really difficult for me because the skin is so dehydrated and crepey now. I notice immediately when something isn't doing enough. I have very high standards here. And this one does. It's creamy, it's hydrating, and over time, I think it's genuinely helped the overall quality of the skin there. So yes, I already have an open one that I'm using every day. There was never a question that I would."
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"Eye products are really difficult for me because the skin is so dehydrated and crepey now. I notice immediately when something isn't doing enough. I have very high standards here. And this one does. It's creamy, it's hydrating, and over time, I think it's genuinely helped the overall quality of the skin there. So yes, I already have an open one that I'm using every day. There was never a question that I would."
YOUR Favourite Beauty Products of the Year (According to You)
"I talked a lot about OneSkin this year and their OS-01 peptide. That peptide neutralizes senescent cells, which destroys healthy cells around it. [...] This particular product has the highest concentration of the OS-01 peptide to combat the signs of aging around the eyes. This product is really nice and rich and just absolutely beautiful. The first time I tried it because they sent it to me in PR, I got online and bought another one the very next day. [...] I use this every morning."
My Winter MORNING Skincare Routine for Mature Skin
"So this one is the OneSkin OS-01 Eye Topical Supplement. [...] And this one I consistently come back to because it's doing more than just moisturizing. It contains their OS1 peptide designed to target senescent cells, which are those zombie cells that contribute to visible aging. I love it because it's rich but not heavy. It's firm without drying. And I never get milia from it, which can sometimes happen around the eyes. Like I have gone through so many of these things I couldn't even tell you."
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"I talk a lot about One Skin because I love that their products go after senescent cells, also called zombie cells that degrade our healthy skin cells as we age. I've probably gone through two or three of the OS1 eye supplements. It's creamy, it's hydrating, and I just love it."
I Asked Skincare Brands for Discount Codes (Black Friday)
"I use this every day. I use this every morning and I have for months and months. It contains the highest level of their OS1 peptide which reduces senescent cells, those pesky zombie cells that terrorize all the healthy skin cells around it."
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"I apply my OneSkin OS-01 Eye Topical Supplement which contains the OS-01 peptide which kills senescent cells. [...] That is like the double espresso shot for my eyes. But they are feeling plumper and more alive."
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"For the record, no one needs an eye cream, except I need an eye cream, and that's all I'm saying on the matter. I'm pretty committed, but this is not your typical eye cream. It uses the same OS-01 peptide as the face version, but it has a higher concentration. Plus, it has extras like Arjgerolene, CoQ10, and caffeine, which deals with puffiness and fine lines. It's firming around that eye area, but it is never greasy, and there is no millia. This has been my go-to for ages."
☀️ Summer Skincare That Actually Works (54 & Glowing!)
"Now, for the record, no one needs an eye cream, except I need an eye cream, and that's all I'm saying on the matter. I'm pretty committed, but this is not your typical eye cream. It uses the same OS-01 peptide as the face version, but it has a higher concentration. Plus, it has extras like Arjgerolene, CoQ10, and caffeine, which deals with puffiness and fine lines. It's firming around that eye area, but it is never greasy, and there is no millia. This has been my go-to for ages."
❄️ Morning Winter Skincare Routine for Mature, Hydrated, Glowing Skin
"I mean I tried it and immediately I got online and bought another one like that day. In fact I also got another one during the Black Friday sale that's waiting for me in California. This is what keeps my eye area hydrated and plump. So whereas the serum is all about the texture and smoothing everything else, this is really about plumping it up. And I have super high hopes for that OS-01 peptide in relation to longer term plumping and reducing of fine lines."
🛍️ From PR to Impulse Buys — ALL the Goodies!
"I use each of these products every single day. I mean, this makes me so happy to get this in PR."
❤️ Beauty Empties | Will I Repurchase or Not?
"I'm on my second bottle of both the face and the eye supplement and I have two more bottles of each standing by. I did stock up during the Black Friday sale. I use these in my morning routine and I'm really really anxious to see the long-term results."
✨ OneSkin Review | OS-01 Peptide That Changed My Routine ✨
"This was designed to thicken the under eye skin area to boost hydration and reduce dark circles as well as those fine lines. But for me, it's all about the texture. Texture is everything. So, I want it to have the right thickness and I want it coupled with hydration and plumpness. That's what I'm looking for. And the very first time I applied this, I immediately got online and I bought another one. And I have used it every day since."
✓Yay
"I'm kind of locked in with OneSkin's OS-01 Eye Topical Supplement. I started using this last year and I've been loving it and I am sticking to it. The OS-01 is one of the latest and most advanced peptides that really help your skin become more resilient to the aging process. It's creamy, which I really like because it's very moisturizing without being heavy. It does absorb beautifully, but at the same time it does plump out the fine lines. It just feels good. It's powerful, love it."
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All 4 takes from Gothamista
Gentle Spring Morning Skincare Routine
"I'm kind of locked in with OneSkin's OS-01 Eye Topical Supplement. I started using this last year and I've been loving it and I am sticking to it. The OS-01 is one of the latest and most advanced peptides that really help your skin become more resilient to the aging process. It's creamy, which I really like because it's very moisturizing without being heavy. It does absorb beautifully, but at the same time it does plump out the fine lines. It just feels good. It's powerful, love it."
2024 Skincare Faves!
"This was also my winter favorites although I kind of started in the summertime. I only put it there because the texture is more creamy and it's more dense, although I'm at a point now where I kind of want that all year round. Right now I kind of need it for me. This has been the perfect day night combination for well aging, slow aging eyes and repair. The OS-01 peptide is one of the latest, newest and most advanced in peptide technology and so that excites me."
Winter Skincare Must-Haves! Big BFCM Deals
"I love that it is a nice rich dense and moisturizing eye cream. This does however absorb really well and dries down really fast, so it is not like this heavy greasy thing at all. It works well under makeup. I think as my skin around here is just feeling like it's getting thinner more brittle, I kind of appreciate the more moisturizing eye creams. [...] There's my love for peptides and they have one of the most advanced interesting and proven peptides in their formulas."
My Ultimate At-Home Facial
"For eyes I usually use my Tretinoin formula but this is a trade-off day so instead I'm going to use from OneSkin their OS-01 Eye Topical Supplement. This is a rich creamy peptide formula with a high concentration of a new peptide OS-01 which claims to be the first scientifically proven to reverse skin's biological age."
✓Yay
"I also was sent the OneSkin OS-01 Eye Topical Supplement and this has been an eye cream that I've been incorporating quite a bit in my routine as well. This was not a product that I thought I would be obsessed with but I do feel like my skin looks so nice since using these and I literally use these every day."
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"I also was sent the OneSkin OS-01 Eye Topical Supplement and this has been an eye cream that I've been incorporating quite a bit in my routine as well. This was not a product that I thought I would be obsessed with but I do feel like my skin looks so nice since using these and I literally use these every day."
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"I also really enjoyed the OneSkin OS-01 Eye Topical Supplement this year. I noticed a big difference when I was using this consistently, but I will say I have used this eye cream more."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Niacinamide

Niacinamide has evidence behind it for redness, uneven tone and supporting the skin barrier, and it is usually well tolerated even by skin that reacts to most things.

Source: DermNet

Humectants and emollients

Ingredients like these draw water into the surface layers and slow how fast it leaves. The evidence is for comfort, softness and hydration rather than for changing the structure of the skin.

Source: DermNet

Peptides

Peptides are short protein fragments meant to signal repair. The evidence for them is thinner than for retinoids or vitamin C, and it varies a lot by the specific peptide, so the category is more promising than proven.

Source: NIH, National Library of Medicine

Frequently asked.

What is OneSkin OS-01 Eye Topical Supplement?

A peptide-rich eye cream formulated with OneSkin's proprietary OS-01 peptide to address fine lines, wrinkles, and skin firmness around the delicate eye area.

Is OneSkin OS-01 Eye Topical Supplement worth it?

Mostly yes. 6 of the 7 gurus who reviewed it give it their stamp of approval, for a Guru Score of 78%.

What is OneSkin OS-01 Eye Topical Supplement's Guru Score?

OneSkin OS-01 Eye Topical Supplement holds a Guru Score of 78%. That is our read on how warmly the experts talk about it, based on the verdicts of 7 expert reviewers we have collected.

Who is OneSkin OS-01 Eye Topical Supplement best for?

OneSkin OS-01 Eye Topical Supplement is generally suited to mature skin.

Cheaper alternatives the gurus rate.

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