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Prequel Universal Skin Solution Dermal Spray for Face and Body.

Prequel Universal Skin Solution Dermal Spray for Face and Body
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Mists & Essences
#11 in Mists & EssencesSee the ranking →
About this product

A stabilized hypochlorous acid spray formulated with electrolyzed water and mineral concentrate, designed to calm irritation and support skin barrier health on face and body.

Full ingredients

Water (Aqua)*, Hypochlorous Acid, Sodium Chloride, Sodium Phosphate, Disodium Phosphate

More from Prequel 27 products · Guru Score 94% →

Guru Score

82%

Yay

11 experts · Strong agreement

What the gurus are saying

The fine mist and reasonable price earn consistent praise, with experts highlighting how hypochlorous acid calms redness, irritation, and rosacea while supporting healing after procedures or gym sessions. One reviewer found it interchangeable with other hypochlorous acid options and prefers a cheaper alternative, though most value the packaging and formula quality at the $17 price point. Those already using tretinoin or other actives may want to time this for evenings, since hypochlorous acid can temporarily reduce antioxidant effectiveness.
Synthesized from 11 expert reviews · most recent take September 2026

What they liked

  • Fine mist that feels like water on skin
  • Fragrance-free and alcohol-free
  • Affordable compared to similar sprays

What they flagged

  • Can deactivate antioxidants like vitamin C

Type

Mists & EssencesSpray & mist

Formula notes

Fragrance-freeNo drying alcohol

Where to buy

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What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

All takes Yay takes Nay takes Mixed takes Hide sponsored
✓Yay
"I currently am using the Prequel hypochlorous acid spray. [...] One of the reasons I like this one is that it comes in a nice mini size that I can use when I'm flying, on the go, and [...] it has a really nice mister as well. I swear once I started using hypochlorous acid, I never looked back. I use it every single morning and night."
All 3 takes from Hyram
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"I feel like the formulas are very comparable to each other. However, I kind of hate the Tower 28 packaging and I really like the Prequel packaging instead, so I've literally dumped my Tower 28 formula into the Prequel spray because this one has such a finer mist compared to the Tower 28 one, which is a little bit more of a harsher, more direct, intense spray. This one is a very fine mist."
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"But this one is so fine. And honestly, the quality feels similar to what I would expect from a $30, $40, or even $50 facial spray to be, but it's only $17. I [...] incorporate hypochlorous acid into my routine as a preventative measure against redness and irritation. For the price point, the ingredients, and the quality of the sprayer, there's no denying it's a really good product. I definitely recommend it."
My On-The-Go Travel Skin Care Routine ✨
"I currently am using the Prequel hypochlorous acid spray. [...] One of the reasons I like this one is that it comes in a nice mini size that I can use when I'm flying, on the go, and [...] it has a really nice mister as well. I swear once I started using hypochlorous acid, I never looked back. I use it every single morning and night."
✓Yay
"The first recommendation is a hypochlorous acid spray, and the one I like a lot is the Prequel Universal Skin Solution. It comes in a 4 oz bottle for around 17 bucks, which is a reasonable price for how long it lasts. It's formulated with a stabilized hypochlorous acid plus electrolyzed water and mineral concentrate, so it's doing a little more than just pure hypochlorous acid. It's also fragrance free and alcohol free, which matters if your skin is already reactive."
All 2 takes from Dr. Aleksandra Brown
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"Hypochlorous acid spray such as the one from Prequel, or really any brand, spray it on the areas, let it dry completely, run the errands, and then maybe go home and shower."
The Skincare Products Nobody Talks About (But Every Dermatologist Uses)
"The first recommendation is a hypochlorous acid spray, and the one I like a lot is the Prequel Universal Skin Solution. It comes in a 4 oz bottle for around 17 bucks, which is a reasonable price for how long it lasts. It's formulated with a stabilized hypochlorous acid plus electrolyzed water and mineral concentrate, so it's doing a little more than just pure hypochlorous acid. It's also fragrance free and alcohol free, which matters if your skin is already reactive."
✓Yay
"The Prequel hypochlorous acid spray is in it. Hypochlorous acid is wonderful if you have any kind of skin irritations. Calms and soothes your skin very nicely."
✓Mixed
"I haven't felt like there's a lot of difference in the hypochlorous acid mists I've tried personally, it's not a complicated product and not one that maybe everyone needs, it's more of a quick spray cleanser. [...] The nozzle and sprayer are great and it's not too expensive, but it is one that I wouldn't go out of my way to buy. [...] It's a great hypochlorous acid mist option, but my favorite is still the one from Pacifica because it's accessible and it's $12."
✓Yay
"I love this one because it's packaged really well. It has a great pH, very simple ingredients, and it's not overpriced. [...] We don't need to be spending like $30 or more on hypochlorous acid, that's insane. [...] It's like a one fix all type of product. It can help acne, rosacea, eczema, sensitive skin, can help fix or repair your skin barrier. It's great to use after the gym to cut down on bacteria on the skin. It's a really, really great addition to any skincare routine."
All 4 takes from The Budget Dermatologist
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"I love this one because it's packaged really well. It has a great pH, very simple ingredients, and it's not overpriced. [...] We don't need to be spending like $30 or more on hypochlorous acid, that's insane. [...] It's like a one fix all type of product. It can help acne, rosacea, eczema, sensitive skin, can help fix or repair your skin barrier. It's great to use after the gym to cut down on bacteria on the skin. It's a really, really great addition to any skincare routine."
Apply Your Skincare In This Order! | Retinoid Skincare Routine
"I use the one by Prequel. This is called the Universal Skin Solution Dermal Spray. This is a really great formulation at a great pH and a super affordable price, even better than many of the other popular ones out there. I just do a quick spritz over the surface of the skin."
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"The best hypochlorous acid spray I've used this year is by Prequel. Very transparent formulation of this product. I love this. You can use hypochlorous acid for so many things, it's one of these products that you should just keep on hand, you have it when you need it. Do not skip this product."
Do You NEED Hypochlorous Acid In Your Skincare Routine? | The Budget Derm Explains
"I've been trying Prequel. This is also under $15. I love that this has the pH listed, it has the percentage of hypochlorous acid in it. I love to live for transparent skincare packaging so this is a must."
✓Yay
"It's a nice hypochlorous acid. This felt really really good. I like it. If you are into hypochlorous acid, this is a good one and that's all I have to say."
✓Yay
"I'm going to go in with the Prequel Universal Skin Solution Dermal Spray. This is hypochlorous acid. This is, I guess, kind of to rewet it. This isn't really a toner but you guys have heard me talk about how much I love this stuff. It's great for any redness. For me, I was dealing with my perioral dermatitis under here, which you can see is getting better. [...] I like to let that dry down just because it can deactivate some of your other skincare products."
All 6 takes from Mixed Makeup
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"This is just a hypochlorous acid spray, and there's a reason for it, it is great for anybody who has skin irritation. For me with peroral dermatitis, and because of my melasma, I have noticed that anytime I get really red, like if I'm irritated, I have redness, or if I spent too much time at the gym, or if I was out in the sun, if I got really hot, I will keep a bottle of this. I also like spraying it on my back so I don't get breakouts."
Pre & Post-Gym Skincare Routine for Clear, Glowing Skin
"This is the hypochlorous acid, they call it Universal Skin Solution Dermal Spray for Face and Body, it's 0.2% hypochlorous acid. I'm obsessed. Every time I'm at Target looking at my own brand and I see Prequel I'm so proud of Dr. Sam Ellis and I have to pick up another bottle because I go through so much of this. [...] I'm putting this on partially for the perioral dermatitis I still have, I'm so red in that area, partially because I get red on my cheeks lately so much more too."
Nighttime Skincare Routine for Perioral Dermatitis & Melasma
"I'm going to go in with the Prequel Universal Skin Solution Dermal Spray. This is hypochlorous acid. This is, I guess, kind of to rewet it. This isn't really a toner but you guys have heard me talk about how much I love this stuff. It's great for any redness. For me, I was dealing with my perioral dermatitis under here, which you can see is getting better. [...] I like to let that dry down just because it can deactivate some of your other skincare products."
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"This one's from Prequel, it's my favorite one out there. It's really affordable, I really just love the way it sprays, it's nice and soothing. I love using hypochlorous acid especially after I work out, like right after the gym when I'm not going directly into the shower. I spray this on, it helps you to just not break out. [...] I especially think it's great for post shave and when you cut yourself."
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"I'm going to go in with this from Prequel, the Universal Skin Solution Dermal Spray. This is not part of the instructions, but whenever I do any kind of treatment I really do like to use it, it just kills any bacteria and it feels good, helps with that redness."
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"I bounce between the Tower 28 and the one from Prequel because I have perioral dermatitis constantly."
✓Yay
"I love it for rosacea. I've been using hypochlorous acid [...] over the last four months and healing has sped up definitely. Things after Botox as well and filler, giving quick sprits of that after, I feel like things are healing a bit more and calming and soothing."
All 2 takes from Caroline Hirons
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"I love it for rosacea. I've been using hypochlorous acid [...] over the last four months and healing has sped up definitely. Things after Botox as well and filler, giving quick sprits of that after, I feel like things are healing a bit more and calming and soothing."
James Welsh and Emma Lewisham: Their Skincare Favourites and The Rise In Celebrity Skincare Brands
"Prequel has something called hypochlorous acid. I love it for rosacea because I'm constantly testing skincare as well, so I'm bound to upset my skin twice a month. But hypochlorous acid in general, over the last four months I've been using it, healing sped up, definitely things after Botox as well and filler, giving it a quick spritz after. I feel like things are healing a bit more, and it's calming and soothing."
✓Yay
"Prequel's hypochlorous acid spray is an amazing product and ingredient in general for breakouts, rosacea, irritated itchy skin, it's like an anti-bac for your face. [...] I've been using this alongside prequel, and compared to the cheaper dupe, prequel gives you a really nice mist rather than it all ending up in your face."
All 5 takes from James Welsh
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"I use this every single day without fail because I've always got rosacea, I'm kind of always breaking out, and it does just calm everything down. [...] It's great for cuts and scrapes, you could use it on your pets if they've got a little cut. [...] There is a little bit of talk how hypochlorous acid can basically render your antioxidants useless, so I personally use this in the evening."
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"It's a really great all rounder for things like acne flare ups. It's antimicrobial, antibacterial, so it helps calm down redness and irritated skin, breakouts. My rosacea has been silent since I've been using it. [...] It's really affordable compared to other ones on the market. I usually do this before any other skincare and just kind of let it dry down, after cleanse and go into it. [...] If you're struggling with redness, skin irritation, breakouts, rosacea, give Hypochlorous Acid a try."
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"If you picked a spot, it's going to help soothe it. This has been my everything for everything. When my rosacea is flaring up, spray on, soothes it. Breakouts, irritated skin, I get really irritated like on my sideburns for some reason. Knowing I have sprays like this, soothing serums, skin barrier repairing moisturizers that are going to help soothe it quicker, I worry about it a lot less. This has hypochlorous acid, sodium chloride, sodium phosphate, disodium phosphate, and electrolyte water."
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"I'm going to use the Prequel Universal Skin Solution Dermal Spray for Face and Body just to help with my brash houseal and irritation then we have to let that sink in and dry on the skin."
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"Prequel's hypochlorous acid spray is an amazing product and ingredient in general for breakouts, rosacea, irritated itchy skin, it's like an anti-bac for your face. [...] I've been using this alongside prequel, and compared to the cheaper dupe, prequel gives you a really nice mist rather than it all ending up in your face."
✓Yay
"I have the Prequel Universal Skin Solution Dermal Spray for Face and Body, which is another great option. I have atopic dermatitis that gets aggravated by my sweat, and that makes me really itchy. I find hypochlorous acid sprays really beneficial, mostly for my body. I don't really use them too often on my face, from time to time I do, but primarily on my body."
All 2 takes from Dr Dray
Is Prequel Skincare Worth It?
"It is a good product [...] if you're on the hunt for a hypochlorous acid spray and I don't really think it's that expensive in general."
Skin Benefits Of Hypochlorous Acid
"I have the Prequel Universal Skin Solution Dermal Spray for Face and Body, which is another great option. I have atopic dermatitis that gets aggravated by my sweat, and that makes me really itchy. I find hypochlorous acid sprays really beneficial, mostly for my body. I don't really use them too often on my face, from time to time I do, but primarily on my body."
✓Yay
"This is the Prequel Universal Skin Solution, it is hypochlorous acid. [...] It's a very gentle refresher for the skin, it's antimicrobial, it's anti-inflammatory, and it's what I use every day in my own clinic to prepare my patient skin for procedures. It helps cleanse the skin."
SponsoredFounder's own brand
All 6 takes from Dr. Sam Ellis
My Sensitive Skin Nighttime Skincare Routine as a Dermatologist | Dr. Sam Ellis
"This is the Prequel Universal Skin Solution, it is hypochlorous acid. [...] It's a very gentle refresher for the skin, it's antimicrobial, it's anti-inflammatory, and it's what I use every day in my own clinic to prepare my patient skin for procedures. It helps cleanse the skin."
Dermatologist's Ultimate Beauty Hacks for Glowing Skin | Dr. Sam Ellis
"One thing I've added to my dermaplaning routine that's not included in the YouTube tutorials I already have out there is I've started incorporating hypochlorous acid, in the beginning to cleanse my face as well as at the end to soothe it, and I've been using the one from my brand Prequel."
Dermatologist Explains Hypochlorous Acid: How to Use it in Your Skincare Routine | Dr. Sam Ellis
"I really love the spray mechanism on this because one issue I found with hypochlorous acid sprays in the past is you don't get a nice fine mist when you spray, it's more of a squirt, and so I really find that this has a beautiful application on the skin. I do want to make it very clear that this is not considered a drug; it is a cosmetic, so we really think of it as calming, soothing, and purifying the skin, but it is not a treatment or cure for things like acne or rosacea."
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"This is so amazing for like sensitive irritated skin. [...] If you have irritated skin, if you have reactive skin, it's just fantastic."
Fix Redness on the Face and Body | Dr. Sam Ellis
"When I was creating Prequel, my skincare brand, I wanted to have a hypochlorous acid spray in there because I recommend it so much and it's something that has done wonders in my own skincare routine."
Introducing Prequel's NEW Hypochlorous Acid Spray, Universal Skin Solution | Dr. Sam Ellis
"Even though I use hypochlorous acid spray in my clinic all the time to prepare my patients for procedures, it's not just a cleanser, it is a multi-purpose spray that you can use in your day-to-day life to accomplish so many things when it comes to skin care. I really wanted a hypochlorous acid spray in Prequel's lineup because of its versatility, and I feel like there are so many people out there who have sensitive skin who want to cleanse their skin, prep their skin, soothe their skin."

Frequently asked.

What is Prequel Universal Skin Solution Dermal Spray for Face and Body?

A stabilized hypochlorous acid spray formulated with electrolyzed water and mineral concentrate, designed to calm irritation and support skin barrier health on face and body.

Is Prequel Universal Skin Solution Dermal Spray for Face and Body worth it?

Mostly yes. 10 of the 11 gurus who reviewed it give it their stamp of approval, for a Guru Score of 82%.

What is Prequel Universal Skin Solution Dermal Spray for Face and Body's Guru Score?

Prequel Universal Skin Solution Dermal Spray for Face and Body holds a Guru Score of 82%. That is our read on how warmly the experts talk about it, based on the verdicts of 11 expert reviewers we have collected.

Who is Prequel Universal Skin Solution Dermal Spray for Face and Body best for?

Prequel Universal Skin Solution Dermal Spray for Face and Body is generally suited to sensitive skin and acne-prone skin.

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