SkinMedica Age Defense Retinol 0.25: a Guru Score of 82%

What the gurus are saying.

Every take we've logged from this product's reviews across YouTube. Click any row to watch the moment they said it.

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✓Yay

"In my practice I actually sell Skin Medica. We have this at 0.3, 0.5, and 1 percent. It comes in an opaque tube, it comes in a pump, it is scentless, and very, very elegant in formulation."

Dr Dray

2.69M subs

✓Yay

"But now that we have this paper showing it gets into the skin, activates the markers of retinoid activity, and shows clinical improvement in the visible signs of photo aging, I can actually recommend this product as a retinol. [...] I feel pretty confident that if you chose it you would at least be getting the benefits of a retinol, [...] although it's got its limitations, since this was a very small study that only enrolled Caucasian skin types and didn't control for the vehicle."

Dr. Sam Ellis

898k subs

✓Yay

"Another retinol product that I really enjoy is the SkinMedica Age Defense Retinol. [...] If you're a beginner, I would start with their 0.25%. This retinol is more of a lotion texture, so it can kind of hit that sweet spot between a serum and the heavier cream. I think that this is probably one of the most recommended products that has a retinol in it that my patients have given to me."

All 2 takes from Dr. Sam Ellis

Dermatologist Explains Retinols for Beginners with Affordable Drugstore Options! | Dr. Sam Ellis

"Another retinol product that I really enjoy is the SkinMedica Age Defense Retinol. [...] If you're a beginner, I would start with their 0.25%. This retinol is more of a lotion texture, so it can kind of hit that sweet spot between a serum and the heavier cream. I think that this is probably one of the most recommended products that has a retinol in it that my patients have given to me."

Best Anti-Aging Skincare Ingredients to Add to Your Skincare Routine (Wrinkles, Dark Spots, & More)

"For over-the-counter retinoids I really like the SkinMedica Age Defense Retinol Complex. This actually comes in a variety of strengths so you can start with a lower potency form of retinol and work your way up as your skin tolerates it, so that's a gentler way to introduce your skin to this powerhouse anti-aging ingredient."

What the evidence says.

Independent of what the gurus think, this is what the published research supports about the main active ingredients here.

Frequently asked.

What is SkinMedica Age Defense Retinol 0.25?

A retinol treatment for visible signs of skin aging, available in three strengths: 0.3%, 0.5%, and 1%.

Is SkinMedica Age Defense Retinol 0.25 worth it?

Yes. All 3 gurus who reviewed it give it their stamp of approval, for a Guru Score of 82%.

What is SkinMedica Age Defense Retinol 0.25's Guru Score?

SkinMedica Age Defense Retinol 0.25 holds a Guru Score of 82%. That is our read on how warmly the experts talk about it, based on the verdicts of 3 expert reviewers we have collected.